PhD Position in Mikrobiologie

Klingt spannend?
Das sind wir:

The Research Training Group (RTG) 2740 which has started on January 1^st 2022, is a research consortium funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation). It consists of 11 research groups focusing on the in situ analysis of micromilieu factors and metabolites in the context of microbial infections (https://www.immunomicrotope.de/). The RTG 2740 is located at Friedrich-Alexander-University (FAU) Erlangen-Nuremberg, one of the largest research universities in Germany.
For our project “Micromilieu control of Salmonella virulence” within the RTG 2740 we are looking for an open and dedicated PhD student with a great interest in microbiology and infection biology research. In cooperation with the group of Prof. Dr. Jonathan Jantsch (University Hospital Cologne), the project aims to investigate the impact of intestinal environmental signals, such as hypoxia, to modulate Salmonella virulence functions. The understanding how Salmonella virulence is triggered in response to intestinal environmental cues might aid the development of anti-virulence strategies.

Your tasks:

• Generation of Salmonella mutants
• Comparative transcriptomics of bacteria and infected host cells
• Cell culture infection models
• Reporter gene studies
• ..and more! 

Comments:

Essential experience/qualifications:

• Successfully completed M.Sc. degree in the field of life sciences (biology, biochemistry, biotechnology, molecular medicine or similar)
• Hands-on experience working with bacteria
• Excellent skills of the English language (spoken and written) incl. presenting research data
• Willing to participate in the supervision of practical courses, Bachelor- and Master students

Additionally beneficial are:

• Molecular pathogenicity research with BSL2 organisms
• Hypoxia research
• Data analysis using R and/or Python, especially transcriptomics
• Molecular biology: cloning, mutagenesis, recombination
• Use of reporters (fluorescence, luminescence)
• Cell culture techniques, e.g. cell lines, organoids
• Microscopy, e.g. CLSM, live-cell imaging