PhD Position in Intravital Imaging of Cerebrospinal Fluid

Universität Bern

Schweiz

 

PhD Position in intravital imaging of cerebrospinal fluid

 

Theodor Kocher Institute, University of Bern

 

The group of Dr. Steven Proulx seeks a qualified and highly motivated individual aiming to pursue a PhD thesis involving in vivo imaging of the cerebrospinal fluid (CSF) and lymphatic systems. The role of the lymphatic system in the clearance of CSF and brain interstitial fluid is an emerging, controversial topic. We have determined that CSF drains exclusively via lymphatics in mice through routes along cranial and spinal nerves (Ma et al, Nature Comm, 2017; Ma et al, J Exp Med, 2019). This finding has led to new concepts regarding the role of cerebrospinal fluid circulation and the immune system in a number of pathologies.

Aufgaben
The Swiss National Science Foundation (SNSF) supported project involves development of new imaging techniques to evaluate lymphatic outflow in mouse models of neurological disorders, including hemorrhagic stroke. An ideal candidate should be motivated to learn and develop new in vivo microscopic techniques, involving near-infrared and two-photon imaging, as well as be interested in establishing and refining mouse models of disease.
Anforderungen
The applicant should have a master's degree in neuroscience, biomedical engineering or a related field and have interest in the fields of neuroimmunology, neuroanatomy and physiology. Previous in vivo experience with rodent models is desired. The candidate must have strong written and oral communication skills in English, while working knowledge of German is a plus.
Wir bieten
The position is available immediately. The TKI offers international state-of-the-art laboratory equipment and a collaborative work environment between several research groups focused on neuroimmunology
 
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. The PhD student will be enrolled in the interfaculty Graduate School for Cellular and Biomedical Sciences at the University of Bern
 
(www.gcb.unibe.ch)
 
with the potential option of enrolling in the Microscopy Imaging Center PhD program
 
(https://www.mic.unibe.ch/phd_program.php).
 
Interessiert?
Für fachliche Auskünfte zur Stelle steht Ihnen....
Please send your CV (including the names of at least two references) with motivation letter to
 
(steven.proulx@tki.unibe.ch)
 
. For further information, please contact by e-mail. Please send your application before March 31st, 2020.


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